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Andrew Pines, MD PGY-2

Andrew graduated from the University of Denver with a degree in Philosophy and Economics. Before medical school, he earned a Master’s degree in Philosophy from KU Leuven, Belgium. He then attended Mayo Clinic School of Medicine at the Arizona campus and, when not studying, worked on neuroscientific educational initiatives and QI projects. Since coming to Brigham, Andrew joined the center for Brain Circuit Therapeutics to investigate neural circuits involved in different symptoms of psychosis. He is interested in neuroimaging, the biological causes of psychosis, molecular effects of psychiatric medications, the relationship between the immune and central nervous systems. Andrew loves things outdoors (mountain biking, backpacking, snowboarding, rock climbing), indoors (poetry, writing, art museums, playing music) and metaphysical doors (also enjoys metaphysical grounds, ceilings, walls, windows, and kitchenware).

Matthew Baum, MD, PhD, D.Phil PGY-3

Matt holds a B.S. and M.S. in Molecular, Cellular, and Developmental Biology from Yale University; an M.Sc. in Neuroscience from Trinity College, Dublin (where he was a George Mitchell Scholar); a D.Phil. in Neuroethics from Oxford University (where he was a Rhodes Scholar); and an M.D. and Ph.D. (in Neuroscience) from Harvard Medical School. He is the author of the book, “The Neuroethics of Biomarkers: What the Development of Bioprediction Means for Moral Responsibility, Justice, and the Nature of Mental Disorder” (published by Oxford University Press), is a past plenary speaker at the annual meeting of the International Neuroethics Society, and has taught medical ethics at Oxford and Harvard. His neuroscientific work at Harvard focused on the complement cascade, and its regulation, in a synaptic pruning hypothesis of schizophrenia; for this work, he received the Sanger Award graduation prize for research related to psychiatry. During residency, he hopes to develop an integrated scientific, neuroethical, and clinical pursuit of immune-molecule dysfunction in psychosis. Matt also enjoys fermentation (intellectual and actual), a collaborative pursuit that has yielded “Microgli-Ale”, a tribute to the brain cells that engulf synaptic components, and a beer to be “engulfed responsibly”.

Yong Hoonk Kim, MD, PhD PGY-3

Yong received a B.S. in Molecular, Cell, and Development Biology summa cum laude and Phi Beta Kappa from the University of California, Los Angeles, where he was selected as an Amgen Scholar. He subsequently received an M.D. and Ph.D. from the University of Pennsylvania Perelman School of Medicine, where he pursued circadian rhythm research in the laboratory of Dr. Mitchell Lazar. Funded by an independent NIH F30 pre-doctoral fellowship, his thesis investigated how 3D chromatin architecture dynamically modulates circadian gene expression, which led to a first-author publication in Science. This paper was highlighted by Science and Genes & Development, and recommended by two members of the Faculty of 1000. In addition, he published a first author review paper in Endocrine Reviews and several co-author publications. He is a recipient of numerous research awards, including the Saul Winegrad Award for Outstanding Dissertation, the highest honor given to biomedical Ph.D. students graduating from Penn. His scientific contribution was recognized by several awards from national and international organizations, including the Keystone Future of Science Fund Scholarship, the Endocrine Society’s Medical Student Achievement Award, and the American College of Neuropsychopharmacology (ACNP) Travel Award. During residency, he hopes to apply functional genomics and chromatin architecture tools to uncover the genetic and epigenetic underpinnings of neuropsychiatric disorders.

Amanda Koire, MD, PhD PGY-3

Amanda holds a B.S. (Molecular Biology) from Pomona College and an M.D. and Ph.D (Quantitative and Computational Biosciences) from Baylor College of Medicine. Her research at Baylor entailed developing computational methods for interpreting rare genetic variants. Her work was funded through the Cancer Prevention Research Institute of Texas (CPRIT) predoctoral fellowship and the Robert and Janice McNair M.D./Ph.D. scholarship and resulted in multiple first-author publications. She has been a speaker at the Pacific Symposium on Biocomputing and her cover article in Human Mutation was recognized as one of the journal’s most downloaded papers in its first year after publication. During residency Amanda’s research at BWH has studied the psychological impact of COVID-19 on pregnant and postpartum women and at Texas Children’s Hospital has aimed to better optimize postpartum depression screening. Her research has been published in BMC Pregnancy and Childbirth, Journal of Psychiatric Research, and Archives of Women’s Mental Health, and has been presented at the Marce of North America and APA conferences, where she was the 2022 APA Medical Student/Resident Poster Competition winner.

Jacinta Leyden, MD PGY-4

Jacinta graduated with distinction from Rice University with a major in Bioengineering and Global Health Technologies. Before medical school, she worked in Blantyre, Malawi developing and teaching a medical device repair workshops at the Polytechnic Institute. She also received awards to work at the WHO, where she developed a tool to evaluate the commercial potential of medical devices in low-resource settings. At Stanford School of Medicine, Jacinta’s scholarly concentration was in health services and policy research, and she focused on the effect of mental health diagnosis on orthopedic outcomes. Currently, her work centers around mental health disparities within ICU patients and trauma informed care. She also has an interest for medical communication and journalism and will be interning at ABC News Medical Unit this summer.


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